Lyophilized Drug Product Cake Appearance: What Is Acceptable?
A) During secondary drying the non-frozen water of the sample is
Freeze-Drying Process Optimization
Impact of Annealing and Controlled Ice Nucleation on Properties of A Lyophilized 50 mg/ml MAB Formulation - Journal of Pharmaceutical Sciences
The Influence of Moisture Content and Temperature on the Long-Term Storage Stability of Freeze-Dried High Concentration Immunoglobulin G (IgG)
Effect of Freezing on Lyophilization Process Performance and Drug Product Cake Appearance.
Lyophilization stabilizes clinical‐stage core‐crosslinked polymeric micelles to overcome cold chain supply challenges - Ojha - 2021 - Biotechnology Journal - Wiley Online Library
Mechanism of collapse of amorphous-based lyophilized cake induced by slow ramp during the shelf ramp process - ScienceDirect
Processes, Free Full-Text
Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine: Molecular Therapy
Freezing and Annealing Phenomena in Lyophilization
Primary Drying Optimization in Pharmaceutical Freeze-Drying: A Multivial Stochastic Modeling Framework
lypholization /Freez drying
Impact of fast and conservative freeze‐drying on product quality of protein‐mannitol‐sucrose‐glycerol lyophilizates